Welcome to Onyx Scientific
Supporting our clients from medicinal chemistry to large scale commercial API production.
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Lead Optimisation
Using our expertise to focus on the delivery of key target compounds for our clients.
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Process Development
Taking your small scale chemical process to a much larger scale to support clinical programs.
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Chemical Synthesis
Providing mg to kg chemistry synthesis of new compounds, APIs, intermediates and many more.
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Scale-up & GMP synthesis
Utilise our MHRA and FDA licensed facilities for GMP synthesis, scale-up and production of APIs.
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Medicinal Chemistry Pre-clinical Phase I Phase II Phase III Commercial

About us

We are a contract manufacturing pharma organisation (CMO) & chemistry contract research organisation (chemistry CRO) that provides pharmaceutical chemistry services to large and emerging pharm & biotech companies across the globe, helping accelerate candidates from discovery to production.

About us

Why Onyx?

This is why you should work with us...
Why Onyx?

Services

Services

Latest Event

Our team will be attending Biotech Outsourcing Strategies (BOS) cmc in Copenhagen, Denmark  13th June 2013 -  why not prearrange a meeting with our team?

Get in touch with our team today…

Latest Event

Latest News & Views

  • ONYX WELCOMES COMMERCIAL EXEC
    27 Feb 2013

    CHEMISTRY services specialist Onyx Scientific has further strengthened its US team with the appointment of another business development professional. Adam Moorhouse joins the contract research and manufacturing [...]

  • ONYX BOLSTERS US TEAM
    18 Nov 2012

    CHEMISTRY CRO Onyx Scientific has strengthened its US presence with the appointment of a Chicago-based business development director. Dan Brisard will oversee the contract manufacturing organisation’s [...]

What our clients say

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      AstraZeneca has worked with Onyx Scientific for many years for early-phase process development and supply of drug substance. This is clearly an area of expertise for Onyx and we continue to be impressed by their excellent technical capability, combined with their strong customer focus and collaborative approach. These qualities result in Onyx routinely meeting or exceeding our project requirements.”

      —Bill Moss, Process Chemistry Director, AstraZeneca

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      As we have moved towards advancing our clinical trial schedule, we have been very pleased with the continued commitment, expertise and support that Onyx Scientific has provided. The team’s flexibility and attention to detail throughout the process, including the adherence to stringent cleaning validation procedures, has assisted us in keeping our project on-track.”

      —Michael Roe, Chemistry & CMC Technical Manager at KalVista Pharmaceuticals KalVista Pharmaceuticals

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      We were delighted with the service provided by Onyx Scientific in conjunction with Reach Separations in carrying out full characterisation and identification. The joint effort allowed us to undertake impurity synthesis to get a positive identification of impurity followed by the purification of a sample by prep LC. The whole process we found to be quick, efficient and cost effective.”

      —Sam Hubbard, Analytical Laboratory Manager at Oxford Analytical Ltd

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      The important thing for us when working with Onyx Scientific was the project was delivered on time and within budget. The team at Onyx communicated well and we were pleased with the quality of the final product.”

      —Dave Hamre, Pharmaceutical Project Manager at Special Products

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      We have worked with Onyx Scientific for a number of years and have been very impressed by their excellent flexibility and responsiveness throughout. They have demonstrated strong technical capability in carrying out PR&D scale up and GMP manufacture on multiple Phase I projects. By utilising their solid state offering alongside the PR&D work, this ensured a very efficient program with respect to salt selection. Vitally for us, their team has supported our application process through fast turnaround on any requests.”

      —Harshad Patel, Project Leader at Pulmagen Therapeutics

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      Onyx Scientific have shown themselves to be technically very capable when it comes to carrying out analytical projects. They took the time to understand our specific requirements and have come up solutions to overcome any challenges. Communication with the team has been particularly excellent given our contacts are easily accessible and contactable at any time. Importantly for us, speed of delivery was exceptional.”

      —David Childs, Director CMC at Shield Therapeutics

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      We were very impressed with the speed at which the team at Onyx Scientific initially responded to our enquiry. We required our compound within six weeks and were delighted to take delivery of our material well within this very tight timescale. Onyx’s team were friendly and knowledgeable, its facilities, equipment and reports were first class and the project on the whole ran incredibly smoothly.”

      —Dr Gavin Donoghue, Pharmaceutical Chemist at Syntopix Group plc

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      Onyx Scientific provided an excellent service, responding very quickly to our needs with the flexibility that the nature of our work requires. They have coped easily with the higher volume of work and the data we are getting is as good as we could ask for. Its team continues to go beyond the call of duty and will enable us to make great progress going forwards. An outstanding experience all around.”

      —Dan Gooding, CEO at Nuformix Ltd

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      We have built a strong relationship with Onyx Scientific based on the team’s responsiveness, quick communications and consistent track record of delivering the right quantity and right quality product on time, even when dealing with complex chemistry.”

      —Sourcing Specialist, Top Five Big Pharma Company

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      Cyclacel has worked closely with Onyx for a number of years. They have provided synthetic chemistry and analytical expertise for our late stage research programs and early development projects such that we could rapidly progress lead candidates through pre-clinical testing and into first in man studies. I have always found Onyx to be very customer focussed, flexible and responsive.”

      —Dr Ben Skead, Head of CMC at Cyclacel

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      We were very pleased with the manner in which Onyx Scientific carried out and delivered our process development and GMP-compliant manufacturing project. The account team all had expertise in chemistry and kept us updated throughout the project before releasing the batch on time.”

      —Dr Nigel Westwood, Drug Supply Manager at Cancer Research UK

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      Having worked with Onyx Scientific for many years, I can say they are one of the finest suppliers in the marketplace. They have delivered a range of different services on time and on budget, without any hidden costs. Their GMP offering has been of particular use to us and we continually find that Onyx delivers excellent value for money.”

      —Dr Daryl Rees, Chief Executive at Salupont Consulting

Contact us

Contact Us
For more information and to find out how our extensive range of services and expertise can help you, get in touch with us today.
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